Ultrasound evaluation of the pregnant uterus in mice
ePoster
Authors: Madison Ives, Augusta University Elisabeth Mellott, Augusta University Rebecca Joseph, Medical College of Georgia Stephanie Stokes, Medical College of Georgia Elsa Parra, University of Tennessee Health Science Center Memphis Natalia Schlabritz-Lutsevich, Advanced Fertility Center Lee Moore, Texas Tech University Health Sciences Center at the Permian Basin James Maher, Augusta University Dept of OB Jessica Faulkner, Medical College of Georgia at Augusta University ,
We used high-frequency ultrasound to evaluate the mouse model and the effect of leptin infusion on the maternal and fetal vasculature .Our results demonstrated increased uterine blood flow in pregnant vs. non-pregnant mice, which is essential for placental function and fetal health. We also anticipate that uterine artery blood flow will decrease in pregnant mice with elevated leptin levels compared to mice with normal leptin levels. This would indicates that leptin influences vascular resistance, which could lead to poor placental function and preeclampsia. By delineating the relationship between leptin, uterine artery resistance, and uterine artery blood flow, we aim to contribute crucial knowledge to the understanding of pregnancy-related vascular complications