Evaluating Erectile Dysfunction Using Novel Ultrasound Techniques
Sunday, April 7, 2024
11:02am – 11:09am
Location: 410
Authors: Priscilla Machado, Thomas Jefferson University Ji-Bin Liu, Thomas Jefferson University Aaron Hochberg, Sidney Kimmel Medical College of Thomas Jefferson University Paul Chung, Thomas Jefferson University Flemming Forsberg, Thomas Jefferson University ,
This study evaluated use of cSMI, mSMI and SWE as novel techniques for evaluating ED in subjects undergoing penile DUS pre and post ICI injection of a vasoactive agent. Spectral Doppler comparison between pre and post injection values showed significant statistical difference for PSV (p = 0.001) but no significant statistical difference for RI (p = 0.06) indicating that potential venous dysfunction could be determine in pre injection ultrasound (flaccid penis). The cSMI and mSMI pixel counts values showed as expected a higher pixel count than CDI and PDI, which correlate with microflow analysis that cSMI and mSMI can depict. Also, no significant statistical difference was found for both modes cSMI (p = 0.60) and mSMI (p = 0.90), which may indicate that the use of these imaging modalities can be use in a no injection ultrasound (flaccid penis) to indicate vascular dysfunction. The evaluation of tissue stiffness using SWE showed no significant statistical difference pre and post injection (p = 0.20), which was a surprising finding, given the physiological changes during erection. The initial results provided encouraging findings in the use of cSMI and mSMI in a no injection ultrasound (flaccid penis) as a way to indicate vascular dysfunction.