Basic Science and Instrumentation Scientific Session 1
Evaluation of Renal Obstruction with Dynamic Contrast-Enhanced Ultrasound
Sunday, April 7, 2024
9:15am – 9:27am
Location: 412
Authors: Kourosh Kalayeh, University of Michigan J. Brian Fowlkes, University of Michigan Man Zhang, University of Michigan Sapan Ambani, University of Michigan William Schultz, University of Michigan Bryan Sack, Michigan Medicine ,
This abstract evaluates the potential of dynamic contrast-enhanced ultrasound (DCEUS) for early detection of kidney obstructions, addressing limitations of existing imaging techniques such as nuclear medicine. Through a study involving adult patients requiring pyeloplasty, DCEUS is utilized to examine renal parenchymal microcirculation in obstructed and unobstructed kidneys. With General Electric clinical ultrasound scanners and custom Python-based software, challenges posed by respiratory motion are addressed to analyze contrast flow dynamics accurately. Notably, among the DCEUS variables, mean transient time (MTT) exhibited significant statistical differences between obstructed and unobstructed kidneys, aligning with contrast dynamics theory. These findings suggest MTT as a potential indicator of kidney obstruction, presenting DCEUS as a viable diagnostic alternative.