Photoacoustic Ultrasound to Predict Responders in the Wound Care Clinic
Monday, April 8, 2024
2:48pm – 2:55pm
Location: 410
Authors: Jesse Jokerst, UC San Diego
This work uses photoacoustic ultrasound, which is a "light in/sound out" technique to map and measure hemoglobin and deoxyhemoglobin. We used photoacoustics to quickly identify people who are responder to treatment in the wound care clinic. This is important because non-responders are usually not identified until many months after initiation of therapy. The rate of PA increase and hence the rate of angiogenesis was able to predict healing times within 30 days from the start of monitoring (power = 88%, alpha = 0.05). The area under the ROC curve was 0.92. This technique is easily done with a portable cart-based system underscoring the value of photoacoustic ultrasound in the wound clinic.