Evaluation Of Decreased Fetal Growth Velocity and Adverse Pregnancy Outcomes In Dichorionic-Diamniotic Twins
Monday, April 8, 2024
12:20pm – 12:30pm
Location: 406
Authors: Leslie Warren, Icahn School of Medicine at Mount Sinai Sonia Khurana, Icahn School of Medicine at Mount Sinai Alexandra Mills, Icahn School of Medicine at Mount Sinai Guillaume Stoffels, Icahn School of Medicine at Mount Sinai Elianna Kaplowitz, Mount Sinai Health System Manasa Rao, Columbia University Isabelle Band, Icahn School of Medicine at Mount Sinai Angela Bianco, icahn school of medicine Chelsea DeBolt, Icahn School of Medicine at Mount Sinai ,
Recent studies have demonstrated an association between decreased fetal growth velocity and adverse pregnancy outcomes, including fetal death, non-reassuring fetal heart rate at birth, and need for urgent cesarean section, in singleton gestations. This was a single-institution retrospective cohort study aimed to assess the association between decreased fetal growth velocity in dichorionic-diamniotic twin gestations and adverse pregnancy outcomes, including NICU admission, preterm birth prior to 34 weeks, and intrauterine fetal demise or neonatal demise. Fetal growth velocity was defined as the slope of the regression line of estimated fetal weight (EFW) percentile as a function of gestational age at each ultrasound. The cut-off value for decreased fetal growth velocity was defined as the 10th percentile of fetal growth velocity among twins without any adverse pregnancy outcome. Results revealed that decreased fetal growth velocity was associated with increased odds of NICU admission and preterm birth prior to 34 weeks in dichorionic-diamniotic twin pregnancies. Future studies may further elucidate if a dynamic, longitudinal model of fetal growth velocity among twin pregnancies may have clinical utility in predicting adverse outcomes, particularly among twins who do not meet criteria for fetal growth restriction.